drugset / Trial / NCT01303003

Evaluation of Addition of Dexamethasone to Transversus Abdominis Plane (TAP) Peripheral Nerve Block

NCT01303003 ↗

RandomizedCrossoverSingle-blindTreatment

Summary

Transversus abdominis plane (TAP) blocks are increasingly being performed after abdominal surgery to provide post operative analgesia. Dexamethasone has demonstrated an ability to prolong the effective duration of analgesia in several different peripheral nerve blocks. The study will examine, in a blinded, prospective and randomized fashion, whether the addition of dexamethasone to TAP blocks similarly prolongs blockade and pain relief. The study will compare local anesthetic with and without the addition of dexamethasone in the TAP block.

Timeline

Start
2010-12
Primary completion
2012-11
Completion
2012-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 4 mg —
Background Bupivicaine Other / unclassified 0.125 % —
Background Bupivicaine Other / unclassified 40 ml —

Indications