drugset / Trial / NCT01309438
A Study of Erythromycin and Rivaroxaban in Study Participants With Normal and Reduced Kidney Function
Parallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the pharmacokinetics and pharmacodynamics of rivaroxaban when administered with erythromycin to study participants with mild or moderate renal impairment compared to the pharmacokinetics and pharmacodynamics of rivaroxaban administered to study participants with normal renal function.
Timeline
- Start
- 2011-02
- Primary completion
- 2012-03
- Completion
- 2012-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Erythromycin | Small molecule | 500 mg | Oral |
| Subject | Rivaroxaban | Other / unclassified | 5 mg | Oral |
| Subject | Rivaroxaban | Other / unclassified | 10 mg | Oral |