Rivaroxaban
Other / unclassified targets F10 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 10 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansions (8) | US (FDA) | XARELTO | — | 2012-11-02 – 2021-08-23 | fda.gov ↗ |
| Approved | US (FDA) | XARELTO | — | 2011-07-01 | fda.gov ↗ |
| Approved | EU (EMA) | Xarelto | — | 2008-09-30 | europa.eu ↗ |
Trials 281 · started per year
Also used as a comparator or background therapy in 110 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 04 trials | ||||||
| Phase 0 | NCT06615596 Comparator | Aug 2025 → Jan 2029 expected | atrial fibrillation | China National Center for Cardiovascular Diseases | Recruiting | No outcome recorded |
| Phase 0 | NCT07032025 Comparator | Jul 2025 → Jul 2027 expected | pulmonary embolism | RenJi Hospital | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT06145269 Comparator | Dec 2023 → Apr 2025 | venous thromboembolism | Assiut University | Unknown | No outcome recorded |
| Phase 0 | NCT02331095 Background | Jan 2015 → Oct 2017 | venous thromboembolism | Ohio State University | Terminated | No outcome recorded |
| Phase 18 trials | ||||||
| Phase 1 | NCT07312851 Background | Jan → Jun 2026 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT06831474 Comparator | Jul 2025 → Apr 2026 overdue | puerperal disorder, venous thromboembolism | Thomas Jefferson University | Recruiting | No outcome recorded |
| Phase 1 | NCT06444178 Comparator | Sep 2024 → Apr 2025 | — | Regeneron Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT06517563 Background | Aug → Dec 2024 | blood coagulation disease | VarmX B.V. | Completed | No outcome recorded |
| Phase 1 | NCT05491460 Comparator | Jul 2022 → Dec 2023 | — | Doasense GmbH | Unknown | No outcome recorded |
| Phase 1 | NCT05152420 Background | Oct 2021 → Feb 2023 | blood coagulation disease | VarmX B.V. | Completed | No outcome recorded |
| Phase 1 | NCT03083704 Background | Feb → Sep 2017 | hemorrhagic disease | Portola Pharmaceuticals | Completed | No outcome recorded |
| Phase 1 | NCT01464450 Comparator | Oct → Dec 2011 | — | Janssen Scientific Affairs, LLC | Completed | No outcome recorded |
| Phase 211 trials | ||||||
| Phase 2 | NCT06220123 Comparator | Feb → Dec 2024 | — | Beijing Suncadia Pharmaceuticals Co., Ltd | Completed | No outcome recorded |
| Phase 2 | NCT05498428 Background | Nov 2022 → Aug 2027 expected | non-small cell lung carcinoma | Janssen Research & Development, LLC | Recruiting | No outcome recorded |
| Phase 2 | NCT04002011 Comparator | Mar 2022 → Jan 2023 | bleeding disorder, vascular-type | Laval University | Withdrawn | No outcome recorded |
| Phase 2 | NCT05088928 Comparator | Mar → May 2022 | COVID-19 | Scotmann Pharmaceuticals | Unknown | No outcome recorded |
| Phase 2 | NCT04755283 Comparator | Feb 2021 → Feb 2024 overdue | atrial fibrillation, stroke disorder | Anthos Therapeutics, Inc. | Active not recruiting | No outcome recorded |
| Phase 2 | NCT04640181 Comparator | Dec 2020 → Jun 2021 | COVID-19 | St. David's HealthCare | Completed | No outcome recorded |
| Phase 2 | NCT03522259 Comparator | Jul 2018 → Dec 2023 | — | Insel Gruppe AG, University Hospital Bern | Completed | No outcome recorded |
| Phase 2 | NCT03172910 Background | May 2017 → Nov 2019 | — | AMAG Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 2 | NCT02303795 Comparator | Aug 2015 → Aug 2020 | heart valve disorder | Hospital do Coracao | Completed | No outcome recorded |
| Phase 2 | NCT03578146 Background | Dec 2012 → Sep 2015 | — | Portola Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT01344954 Comparator | Apr → Dec 2011 | venous thromboembolism | ThromboGenics | Completed | No outcome recorded |
| Phase 2/35 trials | ||||||
| Phase 2/3 | NCT04838808 Comparator | Apr 2021 → May 2022 | myocardial infarction | University of Alberta | Completed | No outcome recorded |
| Phase 2/3 | NCT05515120 Comparator | Jan 2021 → Jan 2022 | bleeding disorder, vascular-type, pulmonary embolism, venous thromboembolism | Mexican Social Security Institute | Completed | No outcome recorded |
| Phase 2/3 | NCT03566303 Comparator | Jul 2018 → Apr 2020 | blood coagulation disease, heart valve disorder, stroke disorder | Hospital Geral Roberto Santos | Terminated | No outcome recorded |
| Phase 2/3 | NCT02829957 Comparator | Sep 2016 → Feb 2020 | menstrual disorder, venous thromboembolism | Indiana University | Completed | No outcome recorded |
| Phase 2/3 | NCT01627665 Comparator | Oct 2011 → Jun 2014 | — | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 314 trials | ||||||
| Phase 3 | NCT07228663 Comparator | Dec 2025 → Jul 2027 expected | venous thromboembolism | McMaster University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06925698 Comparator | Apr 2025 → Apr 2027 expected | Behcet disease, post-thrombotic syndrome, venous thromboembolism | Marmara University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06322953 Comparator | Mar 2025 → Dec 2027 expected | traumatic brain injury | Walton Centre NHS Foundation Trust | Recruiting | No outcome recorded |
| Phase 3 | NCT06370273 Comparator | Nov 2024 → Aug 2028 expected | thrombotic disease | Queen Mary University of London | Recruiting | No outcome recorded |
| Phase 3 | NCT06551402 Comparator | Aug 2024 → Oct 2026 expected | cerebral sinovenous thrombosis | Kafrelsheikh University | Recruiting | No outcome recorded |
| Phase 3 | NCT05718531 Comparator | Feb 2023 → Feb 2025 | vascular ectasia | Assiut University | Unknown | No outcome recorded |
| Phase 3 | NCT06531122 Comparator | Aug 2021 → Sep 2024 overdue | cerebral sinovenous thrombosis | Kafrelsheikh University | Recruiting | No outcome recorded |
| Phase 3 | NCT04284839 Comparator | Jul 2021 → Jun 2027 expected | — | Population Health Research Institute | Recruiting | No outcome recorded |
| Phase 3 | NCT04075240 Comparator | Feb 2021 → Apr 2025 | venous thromboembolism | Sudeep Shivakumar | Completed | No outcome recorded |
| Phase 3 | NCT04673214 Comparator | Dec 2020 → Feb 2021 | COVID-19 | Gilberto Cruz Arteaga | Completed | No outcome recorded |
| Phase 3 | NCT02722447 Comparator | Jan 2017 → Jun 2019 | venous thromboembolism | Walter Ageno | Unknown | No outcome recorded |
| Phase 3 | NCT02387229 Comparator | Mar 2015 → May 2024 | atrial fibrillation | Montreal Heart Institute | Terminated | No outcome recorded |
| Phase 3 | NCT01431456 Comparator | Sep 2013 → Oct 2014 | venous thromboembolism | Martini Hospital Groningen | Completed | No outcome recorded |
| Phase 3 | NCT01924065 Comparator | Aug 2013 → Aug 2017 | atrial fibrillation, stroke disorder | Suleyman Demirel University | Completed | No outcome recorded |
| Phase 449 trials | ||||||
| Phase 4 | NCT06396858 Comparator | Jul 2026 → Aug 2027 expected | ischemic stroke | Brazilian Clinical Research Institute | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06953726 Comparator | Jun 2026 → Oct 2032 expected | atrial fibrillation | VA Office of Research and Development | Recruiting | No outcome recorded |
| Phase 4 | NCT07352358 Background | Jan 2026 → Jul 2028 expected | cerebral sinovenous thrombosis | Xuanwu Hospital, Beijing | Recruiting | No outcome recorded |
| Phase 4 | NCT06650501 Comparator | Jan 2026 → Jan 2030 expected | infective endocarditis, staphylococcal toxemia, staphylococcus aureus infection | McGill University Health Centre/Research Institute of the McGill University Health Centre | Recruiting | No outcome recorded |
| Phase 4 | NCT06212674 Comparator | Oct 2025 → Oct 2027 expected | atrial fibrillation, ischemic stroke | Medical University of Silesia | Recruiting | No outcome recorded |
| Phase 4 | NCT07243080 Comparator | Oct → Nov 2025 overdue | venous thromboembolism | Mayo Hospital Lahore | Recruiting | No outcome recorded |
| Phase 4 | NCT06862726 Comparator | Dec 2024 → Dec 2025 overdue | atrial fibrillation | Les Laboratoires des Médicaments Stériles | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT03129490 Comparator | Apr 2023 → Oct 2027 expected | atrial fibrillation, atrial flutter | Herlev and Gentofte Hospital | Active not recruiting | No outcome recorded |
| Phase 4 | NCT03129555 Comparator | Apr 2023 → Mar 2027 expected | pulmonary embolism, venous thromboembolism | Herlev and Gentofte Hospital | Active not recruiting | No outcome recorded |
| Phase 4 | NCT05180773 Comparator | Jul 2022 → Jun 2026 overdue | peripartum cardiomyopathy | Dennis M. McNamara, MD, MS | Recruiting | No outcome recorded |
| Phase 4 | NCT04794569 Comparator | Nov 2021 → Jan 2024 | post-thrombotic syndrome, venous thromboembolism | Sunnybrook Health Sciences Centre | Terminated | No outcome recorded |
| Phase 4 | NCT05116995 Comparator | Nov 2021 → Nov 2023 | myocardial infarction, thrombotic disease | Nova Scotia Health Authority | Unknown | No outcome recorded |
| Phase 4 | NCT04642430 Comparator | Jul 2021 → Dec 2027 expected | atrial fibrillation | Ottawa Hospital Research Institute | Recruiting | No outcome recorded |
| Phase 4 | NCT06986369 Comparator | May 2021 → Aug 2023 | coronary atherosclerosis | The University of Hong Kong | Completed | No outcome recorded |
| Phase 4 | NCT04724460 Comparator | Feb 2021 → Sep 2024 | neoplasm, venous thromboembolism | Takeshi Morimoto | Completed | No outcome recorded |
| Phase 4 | NCT04757857 Comparator | Sep 2020 → Aug 2022 | COVID-19 | Hospital Alemão Oswaldo Cruz | Terminated | No outcome recorded |
| Phase 4 | NCT04263038 Comparator | May 2020 → May 2028 expected | hemorrhagic disease, lung disorder, pulmonary embolism, venous thromboembolism | Drahomir Aujesky | Recruiting | No outcome recorded |
| Phase 4 | NCT04250116 Background | Apr 2020 → Apr 2025 overdue | atrial fibrillation | Yonsei University | Active not recruiting | No outcome recorded |
| Phase 4 | NCT04169269 Comparator | Jan → Dec 2020 | venous thromboembolism | Florida Orthopaedic Institute | Unknown | No outcome recorded |
| Phase 4 | NCT04023630 Background | Oct 2019 → Sep 2020 | acute coronary syndrome, atrial fibrillation | Second Affiliated Hospital, School of Medicine, Zhejiang University | Unknown | No outcome recorded |
| Phase 4 | NCT03568890 Comparator | Sep 2018 → Aug 2025 overdue | hemorrhagic disease, thrombotic disease, transient ischemic attack | Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec | Active not recruiting | No outcome recorded |
| Phase 4 | NCT03196349 Comparator | Aug 2018 → May 2019 | venous thromboembolism | Duke University | Terminated | No outcome recorded |
| Phase 4 | NCT03463317 Comparator | Feb 2018 → Nov 2024 | atrial fibrillation | Charite University, Berlin, Germany | Completed | No outcome recorded |
| Phase 4 | NCT03413618 Background | Dec 2017 → Jul 2019 | post-thrombotic syndrome, venous thromboembolism | Pirogov Russian National Research Medical University | Completed | No outcome recorded |
| Phase 4 | NCT03266783 Comparator | Dec 2017 → Apr 2025 | venous thromboembolism | Ottawa Hospital Research Institute | Completed | No outcome recorded |
| Phase 4 | NCT03328832 Comparator | Sep 2017 → Sep 2018 | osteoarthritis, knee | Chang Gung Memorial Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03062319 Comparator | Apr 2017 → Jul 2023 | atherosclerosis, atrial fibrillation, ischemic stroke | National Hospital Organization Osaka National Hospital | Terminated | No outcome recorded |
| Phase 4 | NCT02974920 Comparator | Jan 2017 → Nov 2022 | aortic valve insufficiency, aortic valve stenosis, thrombotic disease | Christian Torp-Pedersen | Unknown | No outcome recorded |
| Phase 4 | NCT02885545 Comparator | Sep 2016 → Mar 2018 | chronic kidney disease, stroke disorder | Population Health Research Institute | Withdrawn | No outcome recorded |
| Phase 4 | NCT02559856 Comparator | May 2016 → Nov 2017 | venous thromboembolism | Ottawa Hospital Research Institute | Completed | No outcome recorded |
| Phase 4 | NCT02723981 Background | Apr 2016 → May 2018 | ST-elevation myocardial infarction, intermediate coronary syndrome | IHF GmbH - Institut für Herzinfarktforschung | Withdrawn | No outcome recorded |
| Phase 4 | NCT02701062 Background | Feb 2016 → Apr 2019 | atrial fibrillation | AtriCure, Inc. | Completed | No outcome recorded |
| Phase 4 | NCT02168829 Comparator | Jan 2016 → Aug 2025 | atrial fibrillation, stroke disorder | Ottawa Heart Institute Research Corporation | Completed | No outcome recorded |
| Phase 4 | NCT02666157 Comparator | Jan 2016 → Dec 2018 | atrial fibrillation | National Cheng-Kung University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02610933 Comparator | Nov 2015 → Jan 2019 | calcinosis | Onze Lieve Vrouw Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02549963 Comparator | Oct 2015 → Oct 2017 | atrial fibrillation, stroke disorder | Shulin Wu | Unknown | No outcome recorded |
| Phase 4 | NCT02935855 Comparator | Sep 2015 → Apr 2019 | diabetes mellitus | University of Pavia | Completed | No outcome recorded |
| Phase 4 | NCT02453802 Comparator | Jun 2015 → May 2016 | osteoarthritis, knee | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02376010 Comparator | Apr 2015 → Apr 2018 | atherosclerosis | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT02054936 Comparator | Mar 2014 → Feb 2016 | — | University of Michigan | Withdrawn | No outcome recorded |
| Phase 4 | NCT02024230 Comparator | Jan 2014 → Dec 2018 | atrial fibrillation, coronary artery disorder, stroke disorder | Fujita Health University | Completed | No outcome recorded |
| Phase 4 | NCT01962545 Background | Nov 2013 → May 2017 | atrial fibrillation, coronary artery disorder | Satoshi Shizuta | Completed | No outcome recorded |
| Phase 4 | NCT02331602 Comparator | Jul 2013 → Oct 2015 | atrial fibrillation | Yokohama City University Medical Center | Unknown | No outcome recorded |
| Phase 4 | NCT01812200 Comparator | Oct 2012 → May 2013 | acute coronary syndrome, atrial fibrillation | Medical University of Vienna | Completed | No outcome recorded |
| Phase 4 | NCT01747746 Comparator | Oct 2012 → Oct 2014 | atrial fibrillation, hemorrhagic disease, stroke disorder, venous thromboembolism | Cook County Health | Completed | No outcome recorded |
| Phase 4 | NCT02458729 Comparator | Aug 2012 → Jul 2014 | osteoarthritis, knee | Chang Gung Memorial Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01478282 Comparator | Jan → Dec 2012 | hemorrhagic disease, hyperheparinemia, thrombotic disease | Gines Escolar | Unknown | No outcome recorded |
| Phase 4 | NCT02379663 Comparator | Jan 2012 → Jan 2013 | avascular necrosis, osteoarthritis, hip | Samsung Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT00559988 Background | Feb 2008 → Jun 2013 | arterial occlusion, atrial fibrillation, atrial flutter, stroke disorder | Biotronik, Inc. | Terminated | No outcome recorded |
| Phase not applicable19 trials | ||||||
| — | NCT07497893 Background | Dec 2026 → Nov 2029 expected | atrial fibrillation | Ewha Womans University Mokdong Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07616414 Comparator | May → Dec 2026 expected | atrial fibrillation, thrombotic disease | Fu Wai Hospital, Beijing, China | Not yet recruiting | No outcome recorded |
| — | NCT05993897 Comparator | Aug 2024 → Jun 2025 | atrial fibrillation | Aswan University | Completed | No outcome recorded |
| — | NCT04684212 Comparator | Jun 2024 | atrial fibrillation, stroke disorder | Brian O'Neill MD | Withdrawn | No outcome recorded |
| — | NCT06021808 Comparator | Apr 2024 → Apr 2028 expected | atrial fibrillation | China National Center for Cardiovascular Diseases | Recruiting | No outcome recorded |
| — | NCT06055920 Comparator | Nov 2023 → Jul 2026 overdue | pulmonary embolism | Inari Medical | Active not recruiting | No outcome recorded |
| — | NCT06058130 Comparator | Sep 2023 → Oct 2025 | atrial fibrillation, carotid stenosis, intracranial arteriosclerosis, ischemic stroke | Second Affiliated Hospital, School of Medicine, Zhejiang University | Unknown | No outcome recorded |
| — | NCT05744804 Comparator | Mar → Dec 2023 | myocardial infarction | Sohag University | Unknown | No outcome recorded |
| — | NCT05705076 Comparator | Jan 2023 → Mar 2024 | hyperheparinemia | Mansoura University | Unknown | No outcome recorded |
| — | NCT05701917 Comparator | Jan 2023 → Jun 2026 overdue | post-thrombotic syndrome, venous thromboembolism | Inari Medical | Recruiting | No outcome recorded |
| — | NCT05472766 Comparator | Nov 2022 → Mar 2024 | atrial fibrillation | Sunnybrook Health Sciences Centre | Terminated | No outcome recorded |
| — | NCT05622500 Background | Sep 2022 → Apr 2025 | chronic venous insufficiency, post-thrombotic syndrome | Imperial College London | Terminated | No outcome recorded |
| — | NCT06449469 Background | May 2021 → Apr 2026 overdue | aortic valve stenosis | Rigshospitalet, Denmark | Active not recruiting | No outcome recorded |
| — | NCT03465735 Background | Jan 2017 → Aug 2019 | venous thromboembolism | Mayo Clinic | Terminated | No outcome recorded |
| — | NCT02744092 Comparator | Dec 2016 → Oct 2020 | cancer, pulmonary embolism, thrombotic disease, venous thromboembolism | Alliance Foundation Trials, LLC. | Completed | No outcome recorded |
| — | NCT02704598 Comparator | Mar 2016 → Dec 2018 | venous thromboembolism | Hospital do Servidor Publico Estadual | Unknown | No outcome recorded |
| — | NCT01999179 Background | Jun 2014 → Apr 2019 | neoplasm, venous thromboembolism | Medical College of Wisconsin | Completed | No outcome recorded |
| — | NCT03201367 Comparator | May 2014 → Aug 2016 | portal vein thrombosis | Zagazig University | Completed | No outcome recorded |
| — | NCT02422602 Comparator | Nov 2013 → May 2015 | atrial fibrillation | University Hospital, Montpellier | Completed | No outcome recorded |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 394 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Rivaroxaban | “AF patients with a CHA2DS2-VASc score >2 and no previous history of overt coronary disease, severe peripheral arterial disease (PAD) or major stroke will be registered and...” PMID 27558002 ↗ Aug 2016388“Patients will be chronically treated with NOAC including apixaban (2x5 mg or 2x2.5 mg depending on the dose reduction regimen) or dabigatran (2x150 mg or 2x110 mg depending on...” NCT06212674 ↗ “DOACs (eg Apixaban, dabigatran, edoxaban and rivaroxaban) are recommended by The National Institute for Health and Care Excellence (NICE) for those over 65 with AF and a...” NCT06322953 ↗ “NOAC includes dabigatran 150mg or 110mg twice daily, rivaroxaban 15mg daily with the reduced dose of 10mg daily, apixaban 5mg twice daily with the reduced dose of 2.5mg twice...” NCT01962545 ↗ “edoxaban 60 mg daily (dose reduction to 30 mg, if applicable), apixaban 5 mg twice daily (dose reduction to 2.5 mg, if applicable), dabigatran 110 mg twice daily, or...” NCT03968393 ↗ “Century Clot-guided rivaroxaban prophylactic therapy (2.5 mg twice daily, if the hypercoagulable state, defined as CR ≥24) in combination with standard DAPT could reduce LVT...” NCT06013020 ↗ “For patients with creatinine clearance ≥50 ml/min, oral rivaroxaban 20 mg daily was administered, whereas for patients with creatinine clearance between 30-49 ml/min, oral...” NCT06021808 ↗ “For those randomized to group B (NOAC group), patients will be treated using a registered NOAC (rivaroxaban, apixaban or dabigatran, but preferentionally apixaban) at the dose...” NCT02426944 ↗ “The dosage regimen of anticoagulant was hypodermic injection 0.4 ml low molecular weight heparin per day for 5 days and oral administration of 10 mg Rivaroxaban until one month...” NCT03804697 ↗ “Patients will be treated with warfarin with dose adjusted to goal International Normalized Ratio (INR) of 2-3 or rivaroxaban standard dose (15 mg twice daily for 3 weeks then...” NCT02331095 ↗ “Non-vitamin K antagonist oral anticoagulant therapy (e.g., apixaban, rivaroxaban, dabigatran, or edoxaban) administered according to approved labeling and guideline-recommended dosing.” NCT07497893 ↗ “The PK sub-study is being conducted to assess the blood pharmacokinetics of the three drugs (Sirolimus, Rivaroxaban, Argatroban) eluted from the DESyne BDS Plus after implantation.” NCT05033964 ↗ “Participants in the continuation arm will receive oral anticoagulant drugs such as dabigatran, rivaroxaban, apixaban, warfarin, etc. tailored to their specific risk profiles.” NCT06615596 ↗ “Patients allocated to the DAT group receive either apixaban 5 mg twice daily, edoxaban 60 mg once daily, or rivaroxaban 15 mg once daily with clopidogrel 75 mg once daily.” NCT07583784 ↗ “Apixaban 5mg twice daily (2.5mg twice daily if meets dose-reduction criteria) or rivaroxaban 20mg once daily (15mg once daily if meets dose-reduction criteria) for 2 years” NCT04437654 ↗ “Patients enrolled in the NOAC monotherapy arm would be administered with apixaban 5 mg twice daily or rivaroxaban 20 mg once daily for 2 years after randomization.” NCT04250116 ↗ “Antithrombotic agents include, but are not limited to: warfarin (titrated to international normalised ratio, INR), apixaban, rivaroxaban, aspirin, and clopidogrel.” NCT05622500 ↗ “This study aims to compare the effectiveness of rivaroxaban versus low molecular weight heparin in reducing the incidence of PMVT after bariatric surgery.” NCT06913595 ↗ “Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc.” NCT06055920 ↗ “The patient will receive apixaban 2.5 mg twice daily or rivaroxaban 10 mg once daily during a mean follow-up period of 36 months (12 to 65 months)” NCT03285438 ↗ “Patients who are over 20 years old, have non-valvular atrial fibrillation, and are taking rivaroxaban, apixaban, or edoxaban (active ingredients)” NCT05801068 ↗ “Patients randomized to receive DOAC, at the choice of the investigator: Apixaban 2.5 mg both in day or Rivaroxaban 10 mg once daily.” NCT05198960 ↗ “DOA study medications (Apixaban, Rivaroxaban and Dabigatran) will be prescribed and supplied in the usual setting of patient care” NCT05825573 ↗ “Administration of approved DOACs (e.g., apixaban, rivaroxaban, edoxaban, or dabigatran) at standard stroke prevention dosages.” NCT07609654 ↗ “For rivaroxaban: 10mg once daily for patients with standard 15mg dose, 15mg once daily for patients with standard 20mg dose” NCT07616414 ↗ “Low-molecular-weight heparin bridging to warfarin 3 mg/day, rivaroxaban 10-20 mg/day or dabigatran 110-150 mg twice daily.” NCT07352358 ↗ “Apixaban or dabigatran or edoxaban or rivaroxaban at recommended dosing for stroke prevention in atrial fibrillation.” NCT02998905 ↗ “Patients will be treated with one of the available NOAC drugs; Apixaban, Dabigatran, Edoxaban or Rivaroxaban.” NCT03642509 ↗ “novel oral anticoagulant includes 'dabigatran,Pradaxa®', 'rivaroxaban,Xarelto®', and 'apixaban, Eliquis®'.” NCT02504177 ↗ “Rivaroxaban 20mg orally once daily if CHA2DS2 VASc score 1 or more for males and 2 or more for females.” NCT05993897 ↗ “Rivaroxaban 20mg once daily or 15mg once daily / Dabigatran 110mg twice daily or 150mg twice daily” NCT06058130 ↗ “Apixaban (5mg twice a day) OR Dabigatran (150 mg twice a day) OR Rivaroxaban (20 mg once a day)” NCT05387954 ↗ “using the direct oral anticoagulant Rivaroxaban (brand name: Xarelto) at the recommended dose.” NCT06611319 ↗ “Post-procedural oral anticoagulation is transitioned to rivaroxaban 20 mg once daily (QD).” NCT07032025 ↗ “choice of DOAC (apixaban, dabigatran, edoxaban or rivaroxaban) according to local practice” NCT04700826 ↗ “Dabigatran, Rivaroxaban, Apixaban or Edoxaban at standard dose as recommended by the MRP” NCT05472766 ↗ “any approved direct oral anticoagulant (apixaban, rivaroxaban, edoxaban or dabigatran)” NCT04045665 ↗ “direct oral anticoagulant treatment (apixaban, rivaroxaban, dabigatran, or edoxaban)” NCT01999179 ↗ “Anticoagulation agents includes rivaroxaban, dabigatran, apixaban, and edoxaban.” NCT06057467 ↗ “OAC drugs used: Dabigatran etexilate, Rivaroxaban, Warfarin, other approved VKA” NCT00559988 ↗ “Discontinuation of warfarin, dabigatran, rivaroxaban, apixaban or edoxaban” NCT06401616 ↗ “Anticoagulation with a NOAC (Apixaban, Dabigatran, Edoxaban, Rivaroxaban)” NCT05006287 ↗ “Pharmacogenomic Study on PKD/PKC of Dabigatran Etexilate and Rivaroxaban” NCT01627665 ↗ “Acetylsalicylic acid 100mg once daily plus rivaroxaban 2.5mg twice daily” NCT04619927 ↗ “Rivaroxaban was given for minimum 4 weeks depending on D dimer levels” NCT04935515 ↗ “warfarin, dabigatran etexilate, rivaroxaban, apixaban, edoxaban usage” NCT01924065 ↗ “New oral anticoagulants (NOACs): dabigatran, rivaroxaban, apixaban” NCT02701062 ↗ “to receive either an 18-month or a 6-month rivaroxaban treatment” PMID 39556015 ↗ Nov 2024 “Rivaroxaban 10 mg tablets will take 1 every 24 hours for 10 days” NCT04673214 ↗ “vitamin K antagonist, Apixiban 2.5mg bid or Rivaroxaban 15mg od” NCT02885545 ↗ “warfarin, dabigatran, rivaroxaban, apixaban, or edoxaban” NCT03062319 ↗ “Rivaroxaban: 20 mg once a day or 15 mg once a day” NCT06862726 ↗ “dabigatran, apixaban, edoxaban, rivaroxaban” NCT03759938 ↗ “group B : Rivaroxaban 10 mg plus placebo” NCT05705076 ↗ “Apixaban Dabigatran Edoxaban Rivaroxaban” NCT05292846 ↗ “Xarelto (Rivaroxaban, BAY59-7939)” NCT00973323 ↗ “Intervention Arm: Rivaroxaban” NCT07456085 ↗ “Rivaroxaban (Xarelto)” NCT07011095 ↗ “Rivaroxaban (Xarelto)” NCT03465735 ↗ “Rivaroxaban (Xarelto)” NCT01706146 ↗ “RIVAROXABAN 40 mg” NCT01627665 ↗ “Rivaroxaban 2.5mg” NCT05418803 ↗ “Rivaroxaban” NCT05300555 ↗ “Rivaroxaban” NCT02666742 ↗ |
| Known as | BAY59-7939 | “Comparing the Efficacy and Safety of Rivaroxaban (BAY 59-7939) With Warfarin for the Prevention of Stroke and Non-Central Nervous System Systemic Embolism” NCT00403767 ↗42“One promising therapeutic option is rivaroxaban (BAY 59-7939, Rivaroxaban), an orally administered direct factor Xa inhibitor” NCT02438098 ↗ “Two Strategies of Rivaroxaban [JNJ39039039; BAY-59-7939] and One of Oral Vitamin K Antagonist” NCT01830543 ↗ “Rivaroxaban (Xarelto, BAY59-7939) 10 mg tablet administered once daily (od) in the evening.” NCT00362232 ↗ “Drug: Xarelto (Rivaroxaban, BAY59-7939)” NCT00973245 ↗ “Drug: Rivaroxaban (Xarelto, BAY59-7939)” NCT01507051 ↗ “Drug: Rivaroxaban (Xarelto, BAY59-7939)” NCT02504216 ↗ “Drug: Rivaroxaban (Xarelto, BAY59-7939)” NCT01442792 ↗ “Drug: Rivaroxaban (Xarelto, BAY59-7939)” NCT01853800 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02556203 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00786422 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02367027 ↗ “Xarelto (Rivaroxaban, BAY59-7939)” NCT00973323 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02234843 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT04720092 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01776424 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01145859 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00439777 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02564718 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01684423 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01516814 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02309411 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00439725 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01516840 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00571649 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02313909 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00440193 ↗ “Xarelto (Rivaroxaban, BAY59-7939)” NCT00839163 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00398905 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01674647 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00494871 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00396786 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01839357 ↗ “Xarelto (Rivaroxaban, BAY59-7939)” NCT00395772 ↗ “Rivaroxaban (Xarelto, BAY59-7939” NCT02497716 ↗ “Drug: Rivaroxaban (BAY59-7939)” NCT00332020 ↗ “Drug: Rivaroxaban (BAY59-7939)” NCT01206972 ↗ “Rivaroxaban (BAY59-7939)” NCT00329628 ↗ “Rivaroxaban (BAY59-7939)” NCT00402467 ↗ “Rivaroxaban (BAY59-7939)” NCT01205932 ↗ “Rivaroxaban (BAY59-7939)” NCT00779064 ↗ “Rivaroxaban (BAY59-7939)” NCT00361894 ↗ |
| Known as | Direct Oral Anticoagulant (DOAC) | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05498428 ↗ |
| Known as | JNJ39039039 | “Two Strategies of Rivaroxaban [JNJ39039039; BAY-59-7939] and One of Oral Vitamin K Antagonist” NCT01830543 ↗ |
| Known as | Rivaroxaban (Xarelto) | “Rivaroxaban (Xarelto)” NCT07011095 ↗ |
| Known as | Rivaroxaban accord | ChEMBL registry synonym — accepted as the source's own label CHEMBL198362 ↗ |
| Known as | Rivaroxaban viatris (previously rivaroxaban mylan) | ChEMBL registry synonym — accepted as the source's own label CHEMBL198362 ↗ |
| Known as | Rivaroxabana | “Xarelto 15 mg Rivaroxabana 15 mg” NCT05515120 ↗ |
| Known as | Rovaltro | “Rivaroxaban (Rovaltro®) is a novel oral anticoagulant” NCT04569279 ↗ |
| Known as | Xarelto | “Thromboprophylactic regimens Aspirin®(acetylsalicylic acid, AA, Bayer) 300mg/day or Xarelto® (rivaroxaban, factor Xa-inhibitor, Bayer) 10mg/day will be randomly(according to...” NCT02271399 ↗48“Market approved oral anticoagulation (OAC), such as warfarin (Coumadin), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixiban (Eliquis), edoxaban (Savaysa), or betrixaban (Bevyxxa)” NCT04684212 ↗ “A Randomized, Controlled, Phase 2b Study to Evaluate Safety and Efficacy of Rivaroxaban (Xarelto®) for High Risk People With Mild COVID-19” NCT04504032 ↗ “Blood concentrations of rivaroxaban (Xarelto, Titusville, New Jersey) at 4 weeks were undetectable in 21% patients from Eastern Europe” PMID 33549557 ↗ Feb 2021 “Single administration of oral rivaroxaban in the form of Xarelto® 10mg tablets (Bayer Schering Pharma, Berlin, Germany).” NCT02970773 ↗ “Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®)” NCT03148457 ↗ “novel oral anticoagulant includes 'dabigatran,Pradaxa®', 'rivaroxaban,Xarelto®', and 'apixaban, Eliquis®'.” NCT02504177 ↗ “The two most commonly-used anticoagulants will be compared: apixaban (Eliquis) and rivaroxaban (Xarelto).” NCT06953726 ↗ “Rivaroxaban (Xarelto, BAY59-7939) 10 mg tablet administered once daily (od) in the evening.” NCT00362232 ↗ “a new blood thinner called rivaroxaban (Xarelto) can be used to treat HIT” NCT01598168 ↗ “Drug: Xarelto (Rivaroxaban, BAY59-7939)” NCT00973245 ↗ “Rivaroxaban 10 MG Oral Tablet [Xarelto]” NCT04994223 ↗ “Rivaroxaban 10 MG Oral Tablet [Xarelto]” NCT03522259 ↗ “Drug: Rivaroxaban (Xarelto, BAY59-7939)” NCT01507051 ↗ “Drug: Rivaroxaban (Xarelto, BAY59-7939)” NCT02504216 ↗ “Drug: Rivaroxaban (Xarelto, BAY59-7939)” NCT01442792 ↗ “Drug: Rivaroxaban (Xarelto, BAY59-7939)” NCT01853800 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02556203 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00786422 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02234843 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT04720092 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01776424 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01145859 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02367027 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02309411 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02564718 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01684423 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00439725 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01516814 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00439777 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01516840 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00571649 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00440193 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT02313909 ↗ “Xarelto (Rivaroxaban, BAY59-7939)” NCT00839163 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00398905 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01674647 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00494871 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT01839357 ↗ “Rivaroxaban (Xarelto, BAY59-7939)” NCT00396786 ↗ “Xarelto (Rivaroxaban, BAY59-7939)” NCT00395772 ↗ “Rivaroxaban (Xarelto, BAY59-7939” NCT02497716 ↗ “Rivaroxaban 2.5 MG [Xarelto]” NCT04838808 ↗ “Rivaroxaban 2.5 MG [Xarelto]” NCT05077683 ↗ “Rivaroxaban (Xarelto)” NCT02054936 ↗ “Rivaroxaban (Xarelto)” NCT06978439 ↗ |
| Known as | Xarelto is the brand name for rivaroxaban | “Xarelto is the brand name for rivaroxaban” NCT01478282 ↗ |
| Action | Inhibit | “an oral direct inhibitor of factor Xa” PMID 18579811 ↗ Jun 2008 |
| Modality | Other / unclassified | “direct oral anticoagulant” NCT04794569 ↗ |
| Route | Oral | “10 mg of oral rivaroxaban once daily” PMID 18579811 ↗ Jun 2008 |
| Target | F10 | “the direct factor Xa inhibitor rivaroxaban” NCT01812200 ↗ |