drugset / Trial / NCT06057467
Early Versus Late Initiation of Anticoagulation in Mild-to-moderate AIS Patients With NVAF
RandomizedParallel-groupSingle-blindPrevention
Summary
The goal of this clinical trial is to compare the effectiveness between early and late initiation of anticoagulation therapy in acute ischemic stroke (AIS) patients with non-valvular atrial fibrillation (NVAF). Participants will be 1:1 randomized into early or late initiation group. The primary endpoint is early neurological deterioration (END) before discharge.
Timeline
- Start
- 2023-09-15
- Primary completion
- 2025-10-01
- Completion
- 2026-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Apixaban | Small molecule | — | — |
| Subject | Dabigatran | Unknown | — | — |
| Subject | Edoxaban | Small molecule | — | — |
| Subject | Rivaroxaban | Other / unclassified | — | — |