drugset / Trial / NCT07583784
Abbreviated Antithrombotic Therapy After PCI in Patients With AF and AMI
RandomizedParallel-groupSingle-blindTreatment
Summary
The aim of the study is to compare clinical outcomes between direct oral anticoagulant (DOAC) monotherapy versus dual antithrombotic therapy (DOAC plus clopidogrel) in patients with atrial fibrillation and acute myocardial infarction after percutaneous coronary intervention (PCI).
Timeline
- Start
- 2026-07-01
- Primary completion
- 2031-12-31
- Completion
- 2032-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clopidogrel | Small molecule | 75 mg | — |
| Subject | Rivaroxaban | Other / unclassified | 15 mg | — |
| Subject | Rivaroxaban | Other / unclassified | 20 mg | — |
| Comparator | Apixaban | Small molecule | 5 mg | — |
| Comparator | Edoxaban | Small molecule | 60 mg | — |