drugset / Trial / NCT02066662
Rivaroxaban Compared to Vitamin K Antagonist Upon Development of Cardiovascular Calcification
RandomizedParallel-groupSingle-blindBasic science
Summary
The following trial hypothesis will be proved: In patients with atrial fibrillation and/ or pulmonary embolism standard anticoagulant treatment with coumadin/phenprocoumon is associated with accelerated coronary or valvular calcification as assessed by cardiac computed tomography compared to the new anticoagulant therapy with rivaroxaban.
Timeline
- Start
- 2013-07
- Primary completion
- 2020-03
- Completion
- 2020-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Phenprocoumon | Small molecule | — | Oral |
| Subject | Rivaroxaban | Other / unclassified | 15 mg | Oral |
| Subject | Rivaroxaban | Other / unclassified | 20 mg | Oral |