drugset / Trial / NCT07246005

LVT DURATION: Pilot Study of Anticoagulation Duration for Left Ventricular Thrombus

NCT07246005

Phase 2 Not yet recruiting 120 enrolled Queen Mary University of London
RandomizedParallel-groupOpen-labelTreatment

Summary

The LVT DURATION (Optimal Duration of Anticoagulation for LV Thrombus) is a pilot study planned to assess the practicalities of conducting a randomised control trial (RCT) whilst establishing data around the ideal duration of anticoagulation in the treatment of LV thrombus. The main objectives of the study are: * To assess the practicalities of conducting an RCT with regard to recruitment, retention, and outcome measurement. * To identify the optimal length of anticoagulation in the treatment of LV Thrombus After randomisation participants will: * Continue their prescribed oral anticoagulant for the remainder of the trial * Discontinue their prescribed oral anticoagulant for the remainder of the trial

Timeline

Start
2026-12-01
Primary completion
2027-12-01
Completion
2027-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Apixaban Small molecule
Subject Rivaroxaban Other / unclassified
Subject Warfarin Small molecule

Indications