drugset / Trial / NCT01309581
Use of Ketamine to Enhance Electroconvulsive Therapy (ECT) in Depression
RandomizedParallel-groupDouble-blindTreatment
Summary
The primary objectives of this study are to investigate the potential for ketamine anesthesia to increase the antidepressant efficacy of Electroconvulsive therapy (ECT) and to decrease acute ECT-induced adverse cognitive effects.
Timeline
- Start
- 2010-04
- Primary completion
- 2010-10
- Completion
- 2010-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 1 mg/kg | Intravenous |
| Subject | Ketamine | Small molecule | 2 mg/kg | Intravenous |
| Comparator | Methohexital | Small molecule | 1 mg/kg | Intravenous |