Drugs / Methohexital
Methohexital
also known as
Brevimytal · Brevital sodium · Brietal sod · Methohexital civ · METHOHEXITAL SODIUM · Methohexital sodium salt · Methohexitone · Metohexital · +1 more
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | BREVITAL SODIUM | — | 1998-01-30 | fda.gov ↗ |
| Approved | US (FDA) | BREVITAL SODIUM | — | 1960-06-27 | fda.gov ↗ |
Trials 2 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 41 trial | ||||||
| Phase 4 | NCT04187196 | Apr 2020 → Sep 2022 | atrial fibrillation, atrial flutter | Wake Forest University Health Sciences | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT01567852 | Aug 2011 → Mar 2013 | — | University of New Mexico | Completed | No outcome recorded |
Also used as a comparator or background therapy in 8 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT04022226 Comparator | Oct 2019 → Oct 2020 | — | University of New Mexico | Completed | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT05655754 Comparator | Nov 2022 → Oct 2025 overdue | depressive disorder | Medical University of Vienna | Recruiting | No outcome recorded |
| Phase 4 | NCT01881763 Comparator | Jun 2010 → Mar 2017 | bipolar depression, major depressive disorder | Northwell Health | Completed | No outcome recorded |
| Phase 4 | NCT01907217 Background | May 2008 → Nov 2013 | depressive disorder | St Patrick's Hospital, Ireland | Completed | No outcome recorded |
| Phase not applicable4 trials | ||||||
| — | NCT02624050 Comparator | Aug 2016 → Jan 2018 | hypotensive disorder | Milton S. Hershey Medical Center | Completed | No outcome recorded |
| — | NCT02752724 Comparator | Mar 2016 → Apr 2017 | major depressive disorder | VA Puget Sound Health Care System | Completed | No outcome recorded |
| — | NCT01367119 Comparator | May 2011 → Mar 2012 | depressive disorder | Mayo Clinic | Completed | No outcome recorded |
| — | NCT01309581 Comparator | Apr → Oct 2010 | bipolar depression, major depressive disorder | James Murrough | Terminated | No outcome recorded |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 11 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Methohexital | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02752724 ↗ |
| Known as | Brevimytal | ChEMBL registry synonym — accepted as the source's own label CHEMBL7413 ↗ |
| Known as | Brevital sodium | ChEMBL registry synonym — accepted as the source's own label CHEMBL7413 ↗ |
| Known as | Brietal sod | ChEMBL registry synonym — accepted as the source's own label CHEMBL7413 ↗ |
| Known as | Methohexital civ | ChEMBL registry synonym — accepted as the source's own label CHEMBL7413 ↗ |
| Known as | METHOHEXITAL SODIUM | ChEMBL registry synonym — accepted as the source's own label CHEMBL7413 ↗ |
| Known as | Methohexital sodium salt | ChEMBL registry synonym — accepted as the source's own label CHEMBL7413 ↗ |
| Known as | Methohexitone | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01907217 ↗ |
| Known as | Metohexital | ChEMBL registry synonym — accepted as the source's own label CHEMBL7413 ↗ |
| Known as | Sodium methohexital | ChEMBL registry synonym — accepted as the source's own label CHEMBL7413 ↗ |
| Modality | Small molecule | — CHEMBL7413 ↗ |
| Route | Intravenous | “Methohexital 1 mg/kg IV as indicated for ECT” NCT01309581 ↗ |