drugset / Trial / NCT01367119

Ketamine Anesthesia in Electroconvulsive Therapy

NCT01367119

Completed 38 enrolled Mayo Clinic
RandomizedParallel-groupDouble-blindTreatment

Summary

Does the use of ketamine as the anesthetic medication in electroconvulsive therapy (ECT) accelerate the antidepressant effect of ECT? The study hypothesis was that depressed subjects receiving ECT with ketamine as the anesthetic agent would demonstrate a faster rate of improvement, defined as lower depression ratings after the second ECT than depressed patients receiving ECT with the usual anesthetic agent.

Timeline

Start
2011-05
Primary completion
2012-03
Completion
2012-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ketamine Small molecule 1 mg/kg
Comparator Methohexital Small molecule 1 mg/kg

Indications