drugset / Trial / NCT02752724

Ketamine Anesthesia for Improvement of Depression in ECT

NCT02752724

Completed 52 enrolled VA Puget Sound Health Care System
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this prospective randomized clinical trial is to determine if patients receiving ketamine as a part of general anesthesia during electroconvulsive therapy (ECT) rather than standard of care will have improvement in symptoms of depression after a course of ECT treatments. The investigators hypothesize that utilization of ketamine for induction of general anesthesia during ECT treatments will improve symptoms of depression better than standard care. This study is ONLY open to patients eligible to receive healthcare services through the Department of Veterans Affairs at the VA Puget Sound, which means service in the active military, naval or air service or separation under any condition other than dishonorable. Qualifications for VA health care benefits can be found at va.gov.

Timeline

Start
2016-03
Primary completion
2017-04
Completion
2018-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 1 mg/kg Intravenous
Comparator Methohexital Small molecule 1 mg/kg Intravenous