drugset / Trial / NCT01311778

Study to Test the Safety and Efficacy of Cannabidiol as a Treatment Intervention for Opioid Relapse

NCT01311778

Phase 1 Completed 18 enrolled Hurd,Yasmin, Ph.D.
RandomizedParallel-groupTriple-blindTreatment

Summary

Despite the current available therapies for opioid-dependent patients, most patients relapse. This research project focuses on the development of a novel compound, cannabidiol, to modulate opioid craving in humans based on animal models showing its selective effectiveness to inhibit drug-seeking behavior. The development of a targeted treatment for opioid relapse would be of tremendous medical and public health value.

Timeline

Start
2010-02
Primary completion
2011-10
Completion
2011-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Cannabidiol Other / unclassified 400 mg
Subject Cannabidiol Other / unclassified 800 mg
Background Fentanyl Other / unclassified 0.5 ug/kg
Background Fentanyl Other / unclassified 1 ug/kg

Indications