drugset / Trial / NCT01317927
A Study of Belinostat in Combination With Warfarin in Patients With Solid Tumors or Hematological Malignancies
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the plasma concentration and pharmacodynamics effects of warfarin 5 mg, in the presence or absence of belinostat 1,000 mg/m². Pharmacokinetic evaluation of belinostat 1,000 mg/m² and metabolites in the presence of warfarin 5 mg.
Timeline
- Start
- 2010-12
- Primary completion
- 2015-06
- Completion
- 2015-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Belinostat | Small molecule | 1000 mg/m2 | Intravenous |
| Subject | Warfarin | Small molecule | 5 mg | Oral |