drugset / Trial / NCT01320475

Epidural Levobupivacaine-sufentanil Versus Epidural Levobupivacaine and Intravenous Ketamine

NCT01320475

Phase 4 Terminated 2 enrolled Hopital Foch
RandomizedParallel-groupTriple-blindTreatment

Summary

Thoracic epidural analgesia is often proposed to thoracotomized patients. A local anesthetic and an opioid are generally associated to produce an epidural analgesia. However, opioid epidural administration is frequently associated with adverse effects as nausea, vomiting, urinary retention, ... On the other hand, iv ketamine has been demonstrated to be an effective analgesic. The purpose of the study is to compare the epidural administration of levobupivacaine and sufentanil or the epidural administration of levobupivacaine associated with the iv administration of ketamine.

Timeline

Start
2010-09
Primary completion
2011-07
Completion
2011-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 2 ug/kg Intravenous
Comparator Sufentanil Other / unclassified 50 ug Other

Indications

No indication recorded.