drugset / Trial / NCT01323062
Bavituximab Plus Carbo and Pemetrexed in Chemo-Naive Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Subjects
Phase 1
Completed
26 enrolled
UNC Lineberger Comprehensive Cancer Center
Peregrine Pharmaceuticals · collab
NaSingle-groupOpen-labelTreatment
Summary
This is a non-randomized, open-label Phase 1b trial to establish the safety and recommended phase 2 dose (RP2D) of bavituximab in combination with pemetrexed and carboplatin in subjects with previously untreated stage IV non-squamous non-small cell lung cancer (NSCLC).
Timeline
- Start
- 2011-05
- Primary completion
- 2014-05-14
- Completion
- 2018-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bavituximab | Monoclonal antibody | 3 mg/kg | — |