drugset / Trial / NCT01327677

Safety Study of Analgesia After Craniotomy Surgery With End Tidal (ET) Carbon Dioxide (CO2) Monitoring

NCT01327677 ↗

Phase 4 Completed 137 enrolled Johns Hopkins University
RandomizedParallel-groupOpen-labelTreatment

Summary

This research is being done to compare two methods of giving fentanyl, a narcotic often given to patients following brain surgery and determine if one method has more side effects than the other. Both of these methods are available in the postoperative treatment of pain. This research also is being done to determine if patients receiving narcotic pain medicine will benefit from additional monitoring of carbon dioxide levels. Since narcotic pain medicines can slow down breathing, The investigators want to see if measuring exhaled carbon dioxide levels will help identify a slower breathing rate and improve safety.

Timeline

Start
2011-05
Primary completion
2014-05
Completion
2014-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fentanyl Other / unclassified 20 ug Intravenous
Comparator Fentanyl Other / unclassified 25 ug Intravenous
Comparator Fentanyl Other / unclassified 50 ug Intravenous

Indications

No indication recorded.