drugset / Trial / NCT01341301

Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

NCT01341301 ↗

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this research study is to examine the survival of patients undergoing partially matched hematopoietic stem cell transplant (HSCT) on a new type of treatment approach, which has been developed specifically for patients who have evidence of their disease at the time of transplant. In this research study, a way of strengthening the response of the donor cells against the disease has been developed. Patients will undergo one additional day between the two steps of the transplant which may allow their donor's cells to fight the disease more effectively.

Timeline

Start
2010-05
Primary completion
2013-11-04
Completion
2014-08-07

Drugs

EvaluationDrugModalityDoseRoute
Background Cyclophosphamide Other / unclassified — Intravenous
Background Mycophenolate Mofetil Small molecule — Intravenous
Background Tacrolimus Small molecule — Intravenous