drugset / Trial / NCT01341743
Efficacy Optimizing Research of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy
Phase 4
Unknown
360 enrolled
Nanfang Hospital, Southern Medical University
JiangSu Chia-Tai Tianqin Pharmacy Co.Ltd · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the efficacy and safety of generic entecavir monotherapy or in combination with adefovir for chronic hepatitis B patients with inadequate response to NUC therapy
Timeline
- Start
- 2010-12
- Primary completion
- 2014-06
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Adefovir | Unknown | 10 mg | Oral |
| Comparator | Entecavir | Small molecule | 0.5 mg | Oral |
| Comparator | Entecavir | Small molecule | 1 mg | Oral |