DE-111 Against Timolol Ophthalmic Solution 0.5%

Summary

DE-111 ophthalmic solution will be evaluated for superiority in comparison with Timolol ophthalmic solution 0.5%, in IOP(intraocular pressure ) -lowering effect in primary open-angle glaucoma or ocular hypertension patients, in a multicenter, randomized, double-masked, parallel-group comparison study. Safety will be compared and evaluated as well.

Timeline

Start

2011-05

Primary completion

2012-09

Completion

—

Outcome

Met primary endpoint

registry analysis (superiority or other test); DE-111 vs Timolol; p < 0.001; Mean Difference (Final Values) -1.5 (95% CI -2.2 to -0.9); ANCOVA NCT01342094 ↗

Drugs

Indications