drugset / Trial / NCT01344304

Study of Aprepitant / Fosaprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting (CINV) in Colorectal Cancer Patients - SENRI Trial

NCT01344304

RandomizedParallel-groupOpen-labelPrevention

Summary

The object of this study is to evaluate the superiority of aprepitant therapy with a 5HT3-receptor antagonist, dexamethasone and aprepitant compared to standard therapy with a 5HT3-receptor antagonist and dexamethasone for prevention of nausea and vomiting in first course chemotherapy.

Timeline

Start
2011-04
Primary completion
2013-11
Completion
2015-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Aprepitant Other / unclassified 80 mg Oral
Subject Fosaprepitant Other / unclassified 150 mg Intravenous

Indications