Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing

Summary

Main objective : Show that treatment with metformin in patients with type 2 diabetes has an effect on alternative splicing of the insulin receptor. Secondary objective : demonstrate that the effect on the ratio A/isoform B isoform with discontinuation of treatment with metformin can be réversé by the resumption of metformin treatment.

Timeline

Start

2011-05

Primary completion

2011-11

Completion

2012-01

Drugs

Indications