Lactic Acidosis During Entecavir(ETV)Treatment

Summary

The purpose of this study is to investigate whether entecavir treatment increases the incidence of lactic acidosis compared to another nucleoside/nucleotide reverse transcriptase inhibitors (NRTI), lamivudine, and/or no NRTI treatment, in patients with cirrhosis or hepatic failure whose Model for End stage Liver Disease (MELD) scores are over 18.

Timeline

Start

2011-05

Primary completion

2013-09

Completion

2013-09

Drugs

Indications