drugset / Trial / NCT01368003

STA-9090 in Castration-Resistant Prostate Cancer With Assessment of Androgen Receptor Pathway Signaling

NCT01368003

Phase 2 Withdrawn Toni Choueiri, MD
RandomizedParallel-groupOpen-labelTreatment

Summary

In this research study, the investigators are looking to determine the safety and efficacy of an investigational drug, STA9090 alone and in combination with dutasteride for the treatment of castrate resistant prostate cancer. STA9090 may cause the growth of cancer to slow down or shrink by targeting proteins required for the cancer to grow. The investigators are also looking to determine whether the use of dutasteride to lower male hormone levels will enhance the effect of STA9090 in the treatment of castrate resistant prostate cancer.

Timeline

Start
2011-04
Primary completion
2012-11
Completion
2012-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Dutasteride Small molecule 3.5 mg Oral
Subject Ganetespib Small molecule 200 mg/m2 Intravenous