drugset / Trial / NCT01369719
Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload
RandomizedParallel-groupDouble-blindTreatment
Summary
Thalassemic patients often suffer from iron overload due to frequent blood transfusion. Oral iron chelators reduce iron overload in transfusion dependent patients. The aim of this study is to compare the efficacy and safety of osveral and desferal in transfusional iron overload patients with β-Thalassemia and intermediate Thalassemia in Bandarabbas.
Timeline
- Start
- 2010-02
- Primary completion
- 2011-01
- Completion
- 2011-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Deferasirox | Unknown | 20 mg/kg | Oral |
| Comparator | Deferoxamine | Other / unclassified | 40 mg/kg | Subcutaneous |
| Comparator | Deferoxamine | Other / unclassified | 50 mg/kg | Subcutaneous |