drugset / Trial / NCT01372085
Single Dose Study in Healthy Participants to Investigate the Safety and Absorption of LY2584702
RandomizedSingle-groupDouble-blindTreatment
Summary
This is a single-centre, placebo-controlled, two-part study in healthy participants. Part A will be a single dose, single period, placebo-controlled pilot study to explore the safety, tolerability, absorption and pharmacodynamic \[effect of drug on a biological marker-phospho-S6 (pS6) levels in skin biopsies\] of a single dose of 25 milligrams (mg) LY2584702 Reference formulation (RF). Part B is a single dose, placebo-controlled, 4-period crossover study to primarily evaluate the absorption of the Test Formulation (TF) in comparison with the (RF) of LY2584702.
Timeline
- Start
- 2011-06
- Primary completion
- 2011-09
- Completion
- 2011-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LY2584702 | Small molecule | 10 mg | Oral |
| Subject | LY2584702 | Small molecule | 25 mg | Oral |
| Subject | LY2584702 | Small molecule | 50 mg | Oral |
Indications
No indication recorded.