drugset / Trial / NCT01375400

Effect of Aspirin at the Acute Phase of Cerebral Ischemic Event.

NCT01375400

Unknown 50 enrolled Central Hospital, Nancy, France
NaSingle-groupOpen-labelTreatment

Summary

Aspirin is the only anti-platelet medication used at the acute phase of ischemic stroke. The investigators would like to study laboratory effect of the first oral 300 mg dose of aspirin, given at hospital, after an ischemic event. The principal hypothesis is that platelet activity would be able to recover during this day and could lead to ischemic recurrences. Two blood samples are accomplished. The first 2 hours after aspirin intake and the second 23 hours after. Photometric aggregometry are performed with arachidonic acid and collagen induced platelet aggregation, measure of thromboxan B2 levels and reticular platelets count.

Timeline

Start
2010-12
Primary completion
2011-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule 300 mg Oral

Indications