drugset / Trial / NCT01377389

Ipilimumab + Androgen Depravation Therapy in Prostate Cancer

NCT01377389

NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to learn if ipilimumab in combination with either Lupron® (leuprolide), Zoladex® (goserelin), or Firmagon® (degarelix) can affect prostate-specific antigen (PSA) levels in patients with prostate cancer. Researchers also want to learn if these drug combinations affect the body's immune system. The safety of these drug combinations will also be studied.

Timeline

Start
2011-06-17
Primary completion
2017-04-07
Completion
2017-04-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Degarelix Other / unclassified 80 mg Subcutaneous
Subject Goserelin Other / unclassified 3.6 mg Subcutaneous
Subject Ipilimumab Monoclonal antibody 10 mg/kg Intravenous
Subject Leuprolide Other / unclassified 7.5 mg Intramuscular

Indications