drugset / Trial / NCT01385631

Ezetimibe In Addition To Atorvastatin Therapy On The Plaque Composition In Patients With Acute Myocardial Infarction.

NCT01385631

Phase 4 Completed 87 enrolled Odense University Hospital
RandomizedParallel-groupTriple-blindDiagnostic

Summary

The purpose of the study is to examine the effect of the cholesterol lowering agent Ezetimibe when used in addition to optimal treatment with Atorvastatin in patients with acute ST-Elevation Myocardial Infarction (STEMI) who have not been in prior statin therapy. An area with arteriosclerosis not demanding intervention in a coronary vessel other than the infarct related is used as measuring point and is examined at time of the infarction and after 12 month using intravascular ultrasound and optical coherence tomography. At the same time the same techniques are used to examine the implanted stent.

Timeline

Start
2011-06
Primary completion
2014-06
Completion
2014-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Ezetimibe Unknown 10 mg