drugset / Trial / NCT01389557

Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra

NCT01389557

Phase 4 Completed 77 enrolled Indonesia University
NaSingle-groupSingle-blindTreatment

Summary

Artemisinin-based combination therapy (ACT) has been known to be controversial for stopping malaria transmission. The addition of primaquine (PQ) - the only drug commercially available that kills mature transmission stage - to such treatments might be necessary to eliminate this stage. A study is conducted to evaluate the efficacy of dihydroartemisinin-piperaquine (DHP) regimens with PQ on malaria transmission on a community wide level in Lempasing, Lampung, Sumatra.

Timeline

Start
2011-02
Primary completion
2011-11
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Subject ARTENIMOL Small molecule 40 mg
Subject Primaquine Small molecule 0.75 mg/kg
Subject piperaquine Small molecule 320 mg

Indications