Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Forehead and Frown Lines

Completed 175 enrolled Allergan

RandomizedParallel-groupTriple-blindTreatment

Summary

This study evaluated the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of forehead lines (facial rhytides) when also administered to frown lines (glabellar rhytides).

Timeline

Start: 2011-06-01
Primary completion: 2011-10-18
Completion: 2012-02-28

Publications

Background Solish N, Rivers JK, Humphrey S, Muhn C, Somogyi C, Lei X, Bhogal M, Caulkins C. Efficacy and Safety of OnabotulinumtoxinA Treatment of Forehead Lines: A Multicenter, Randomized, Dose-Ranging Controlled Trial. Dermatol Surg. 2016 Mar;42(3):410-9. doi: 10.1097/DSS.0000000000000626.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Botulinum toxin type A	Protein / enzyme biologic	30 iu	Other
Comparator	Botulinum toxin type A	Protein / enzyme biologic	40 iu	Other

Indications

No indication recorded.