Melatonin Treatment for Tardive Dyskinesia in Schizophrenia

Summary

This is a double-blind, randomized, placebo-controlled trial of melatonin as an add-on therapy to antipsychotics will be performed to examine the effects of melatonin on tardive dyskinesia symptoms and cognitive deficits in 120 patients with established tardive dyskinesia (TD). This study addresses a free radical hypothesis of TD.

Timeline

Start

2008-09

Primary completion

2011-04

Completion

2011-05

Drugs

Indications