drugset / Trial / NCT01392755
A Study to Evaluate The Effects of Two Different Meal Types, Omeprazole And Ranitidine On Danoprevir Pharmacokinetics When Coadministered With Ritonavir in Healthy Volunteers
RandomizedSingle-groupOpen-labelTreatment
Summary
This randomized, open-label study will evaluate the effect of food, and the effect of omeprazole and ranitidine on danoprevir co-administered with ritonavir. Volunteers will be assigned to one of two treatment groups. Volunteers in both groups will receive oral doses of danoprevir and ritonavir. In addition, volunteers in group 2 will receive oral doses of omeprazole and ranitidine. The anticipated time of the study is approximately 6 weeks.
Timeline
- Start
- 2011-07
- Primary completion
- 2011-09
- Completion
- 2011-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Omeprazole | Other / unclassified | — | Oral |
| Subject | Ranitidine | Unknown | — | Oral |
| Subject | danoprevir | Small molecule | — | Oral |
| Background | Ritonavir | Other / unclassified | — | Oral |
Indications
No indication recorded.