drugset / Trial / NCT01399515

Efficacy and Safety of Oral Valproic Acid for Retinitis Pigmentosa

NCT01399515

Phase 2 Completed 200 enrolled Seoul National University Hospital
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of oral valproic acid to slow the progression of visual function and/or to improve the visual function in patients with retinitis pigmentosa (RP). Enrolled subjects in valproic acid group will be treated with oral valproic acid 500mg daily for 48 weeks. Visual function and safety will be assess before and after treatment (48 weeks) between valproic acid and control groups.

Timeline

Start
2011-03
Primary completion
2013-08
Completion
2015-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Valproic Acid Small molecule 500 mg Oral

Indications