drugset / Trial / NCT01401179
Antibiotics Study in Preterm Premature Rupture of the Membranes
RandomizedFactorialSingle-blindTreatment
Summary
The purpose of this study is to compare the efficacy on maternal infection, chorioamnionitis and neonatal morbidity and mortality, and to review the evidence and provide recommendations on the use of antibiotics in PPROM.
Timeline
- Start
- 2005-04
- Primary completion
- 2010-04
- Completion
- 2010-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clarithromycin | Small molecule | 500 mg | Oral |
| Comparator | Erythromycin | Small molecule | 250 mg | Oral |
| Comparator | Cefazolin | Small molecule | 1 g | Intravenous |