Hydrogen Peroxide and Nitrite Reduction in Exhaled Breath Condensate of COPD Patients

Summary

The aim of the study is to investigate the effect of inhaled apocynin on ROS (reactive oxygen species) and NOS (reactive nitrogen species) synthesis in 13 COPD patients. Effects of nebulized apocynin (0.5 mg/ml, 6 ml) were assessed in exhaled breath condensate (EBC) after 30, 60 and 120 minutes.

Timeline

Start

2010-10

Primary completion

2011-01

Completion

2011-04

Drugs

Indications