Sublingual Misoprostol for Induction of Labor

Phase 4 Completed 150 enrolled Professor Fernando Figueira Integral Medicine Institute Maternidade Escola Assis Chateaubriand · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to compare effectiveness and safety of a sublingual misoprostol 12,5 mcg with vaginal misoprostol 25 mcg for induction of labour with an alive and term fetus.

Timeline

Start: 2014-07-01
Primary completion: 2016-11-30
Completion: 2016-11-30

Publications

Gattas DSMB, de Amorim MMR, Feitosa FEL, da Silva-Junior JR, Ribeiro LCG, Souza GFA, Souza ASR. Misoprostol administered sublingually at a dose of 12.5 mug versus vaginally at a dose of 25 mug for the induction of full-term labor: a randomized controlled trial. Reprod Health. 2020 Apr 10;17(1):47. doi: 10.1186/s12978-020-0901-8.
Gattas DSMB, da Silva Junior JR, Souza ASR, Feitosa FE, de Amorim MMR. Misoprostol administered sublingually at a dose of 12.5 mug versus vaginally at a dose of 25 mug for the induction of full-term labor: a randomized controlled trial protocol. Reprod Health. 2018 Apr 18;15(1):65. doi: 10.1186/s12978-018-0508-5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Misoprostol	Other / unclassified	12.5 ug	Subcutaneous
Comparator	Misoprostol	Other / unclassified	25 ug	Subcutaneous

Indications

No indication recorded.