drugset / Trial / NCT01408641

Topiramate for Alcohol Use in Posttraumatic Stress Disorder

NCT01408641 ↗

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Alcohol abuse and dependence (alcohol use disorders, AUDs) and posttraumatic stress disorder (PTSD) are both prevalent in Veterans. Treating AUDs in Veterans with PTSD may be more difficult than treating AUDs in the general population. The FDA-approved medication topiramate has been shown to improve drinking outcomes in people with AUDs. Topiramate has also improved symptoms in people with PTSD. This study is designed to investigate whether topiramate will improve drinking outcomes in Veterans with PTSD.

Timeline

Start
2012-09
Primary completion
2013-07
Completion
2013-08

Outcome

Outcome not reported

Stopped: “Principal Investigator was deployed overseas”

Drugs

EvaluationDrugModalityDoseRoute
Subject Topiramate Small molecule 400 mg —