drugset / Trial / NCT01409369

A Study on The Effect of Multiple Doses of Activated Charcoal on The Pharmacokinetics of a Single Dose of RO4995819

NCT01409369

Phase 1 Completed 26 enrolled Hoffmann-La Roche
Non-randomizedCrossoverOpen-label

Summary

This open-label, two period crossover study will evaluate the effect of multiple doses of activated charcoal on the pharmacokinetics of a single oral dose of RO4995819 in healthy volunteers. Each enrolled subject will receive two single oral doses of RO4995819 separated by a wash-out period of up to 9 weeks. In period 1, subjects will receive concomitantly with the single dose of RO4995819 multiple oral doses of activated charcoal until Day 7. In period 2, only a single dose of RO4995819 but no activated charcoal will be administered.

Timeline

Start
2011-08
Primary completion
2012-02
Completion
2012-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Activated Charcoal Other / unclassified Oral
Subject RO4995819 Small molecule Oral

Indications

No indication recorded.