drugset / Trial / NCT01417403
Hydroxychloroquine in Treating Patients With Solid Tumors Undergoing Radiation Therapy for Bone Metastases
Phase 1
Terminated
10 enrolled
Virginia Commonwealth University
National Cancer Institute (NCI) · collab
NaSingle-groupOpen-labelTreatment
Summary
This phase I trial studies the side effects and best dose of hydroxychloroquine in treating patients with solid tumors undergoing radiation therapy for bone metastases. Drugs, such as hydroxychloroquine, may make tumor cells more sensitive to radiation therapy
Timeline
- Start
- 2011-08
- Primary completion
- 2014-07
- Completion
- 2014-07
Outcome
Outcome not reported
Stopped: “Recently published data that has shown HCQ to be safe when combined with chemo and or radiation at even higher doses than what is used in this study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydroxychloroquine | Small molecule | — | Oral |