Evaluate Onset of Action of a Fast Release Aspirin

NCT01420094 ↗

Phase 3 Completed 510 enrolled Bayer

RandomizedParallel-groupTriple-blindTreatment

Summary

To compare the safety and efficacy (onset, duration of relief and overall efficacy) of a single dose of a fast release formulation of aspirin 1000 mg compared to acetaminophen 1000 mg and placebo for relief of pain following extraction of impacted third molars.

Timeline

Start: 2011-06-16
Primary completion: 2011-09-08
Completion: 2011-09-08

Publications

Voelker M, Schachtel BP, Cooper SA, Gatoulis SC. Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain. Inflammopharmacology. 2016 Feb;24(1):43-51. doi: 10.1007/s10787-015-0253-0. Epub 2015 Nov 24.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Acetaminophen	Small molecule	1000 mg	Oral
Subject	Acetylsalicyclic acid	Unknown	1000 mg	Oral

Indications

No indication recorded.