drugset / Trial / NCT01421472
A Trial of Preoperative MM-121 With Paclitaxel in HER2-negative Breast Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
To demonstrate whether addition of MM-121 to paclitaxel is more effective than treatment with paclitaxel alone, when administered as part of the neoadjuvant treatment in Her2 negative locally advanced operable breast cancer patients.
Timeline
- Start
- 2011-08
- Primary completion
- 2013-12
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Seribantumab | Monoclonal antibody | 20 unknown | Intravenous |
| Background | Paclitaxel | Small molecule | — | Intravenous |