drugset

drugset / Trial / NCT01429272

Minocycline and Aspirin in the Treatment of Bipolar Depression

NCT01429272 ↗

Phase 3 Completed 99 enrolled Laureate Institute for Brain Research, Inc. Stanley Medical Research Institute · collab University of Oklahoma · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to determine whether minocycline and aspirin are effective in the treatment of depression in individuals with bipolar disorder.

Timeline

Start: 2011-09
Primary completion: 2015-08
Completion: 2015-09

Publications

Savitz J, Preskorn S, Teague TK, Drevets D, Yates W, Drevets W. Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial. BMJ Open. 2012 Feb 22;2(1):e000643. doi: 10.1136/bmjopen-2011-000643. Print 2012.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Aspirin	Small molecule	81 mg	Oral
Comparator	Minocycline	Small molecule	100 mg	Oral

Indications