Clinical Study Evaluating Safety and Efficacy of Fluticasone Furoate and Fluticasone Propionate in People With Asthma

Summary

A randomised, double-blind, double-dummy, placebo controlled multi-centre study to evaluate the efficacy and safety of fluticasone furoate inhalation powder and fluticasone propionate inhalation powder in the treatment of asthma in adults and adolescents not currently treated with inhaled corticosteroids

Timeline

Start

2011-09

Primary completion

2012-09

Completion

2012-09

Outcome

Missed primary endpoint

registry Placebo vs FF 50 µg OD; p = 0.430; Mean Difference (Final Values) 0.037 (95% CI -0.055 to 0.128); ANCOVA NCT01436110 ↗

Publications

• O'Byrne PM, Jacques L, Goldfrad C, Kwon N, Perrio M, Yates LJ, Busse WW. Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma. Respir Res. 2016 Nov 24;17(1):157. doi: 10.1186/s12931-016-0473-x.

Drugs

Indications