drugset / Trial / NCT01441349
Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare the efficacy of Simvastatin and Irinotecan/Cisplatin chemotherapy with Irinotecan/Cisplatin chemotherapy alone in Extensive disease-small cell lung cancer.
Timeline
- Start
- 2011-08
- Primary completion
- 2022-10-31
- Completion
- 2022-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Simvastatin | Small molecule | 40 mg | Oral |
| Background | Cisplatin | Other / unclassified | 30 mg/m2 | Intravenous |
| Background | Irinotecan | Small molecule | 65 mg/m2 | Intravenous |