drugset / Trial / NCT01451489

The Efficacy and Safety of Tacrolimus in Treated Refractory Focal Segmental Glomerulosclerosis

NCT01451489

Terminated 70 enrolled Nanjing University School of Medicine
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective,multicentre study to compare the efficacy, safety, tolerability and relapse of FK506 versus CTX in the treatment of severe Focal Segmental Glomerulosclerosis (FSGS).

Timeline

Start
2011-10-13
Primary completion
2016-03-23
Completion
2016-10-29

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclophosphamide Other / unclassified 750 mg/m2
Subject Tacrolimus Small molecule 0.05 mg/kg
Subject Tacrolimus Small molecule 0.1 mg/kg