drugset / Trial / NCT01451632

A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers

NCT01451632

Phase 1 Completed 48 enrolled Merrimack Pharmaceuticals Sanofi · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study was to evaluate the safety and tolerability of escalating doses of the MM-121 plus cetuximab and the MM-121 plus cetuximab plus irinotecan combination.

Timeline

Start
2011-10
Primary completion
2013-11
Completion
2014-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetuximab Monoclonal antibody Intravenous
Subject Irinotecan Small molecule 180 mg/m2 Intravenous
Subject Seribantumab Monoclonal antibody Intravenous