drugset / Trial / NCT01451840
Efficacy of Alkalinized Lidocaine Compared to Remifentanil on the Incidence of Coughing During Emergence of Anesthesia
Completed
85 enrolled
University of Montreal Hospital Centre (CHUM)
Centre de Recherche du Centre Hospitalier de l'Université de Montréal · collab
RandomizedParallel-groupDouble-blindPrevention
Summary
This study is designed to compare the effects of alkalinized lidocaine in the endotracheal tube cuff to a bolus dose of remifentanil given prior to the emergence of anesthesia: * on the incidence of perioperative coughing * on the time needed for the emergence of a desflurane-based anesthesia * on the incidence of sore throat after extubation. The investigators hypothesis is that the use of alkalinized lidocaine in the endotracheal tube cuff will reduce the incidence of perioperative coughing after a desflurane-based anesthesia.
Timeline
- Start
- 2012-01
- Primary completion
- 2012-10
- Completion
- 2012-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alkalinized lidocaine | Unknown | — | Other |
| Comparator | Remifentanil | Small molecule | 0.25 ug/kg | Intravenous |
Indications
No indication recorded.