drugset / Trial / NCT01462838

Immune Therapy of HPV-induced Cancers

NCT01462838

Phase 1/2 Completed 26 enrolled Oryx GmbH & Co. KG
NaSingle-groupOpen-labelTreatment

Summary

Patients with advanced HPV- and p16INK4a-positive cancers will receive the peptide P16\_37-63 in combination with Montanide® ISA-51 VG so that an immune response directed against the tumor cells can be induced. The aim is to show that vaccination with P16\_37-63 is safe and can induce or enhance immune responses against p16INK4a.

Timeline

Start
2011-08
Primary completion
2015-01
Completion
2015-05

Drugs

EvaluationDrugModalityDoseRoute
Subject P16_37-63 Peptide 100 ug Subcutaneous
Background incomplete Freund's adjuvant Other / unclassified 0.3 ml