drugset / Trial / NCT01478308

Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer

NCT01478308 ↗

NaSingle-groupOpen-labelTreatment

Summary

This study is being conducted to determine the effectiveness of standard 3 weekly treatments using docetaxel and prednisone with metformin in patients with castration-resistant metastatic prostate cancer. It is also being conducted to determine the levels of toxicity of metformin when added to every 3 weekly docetaxel treatments in patients with endocrine resistent, metastatic prostate cancer.

Timeline

Start
2011-06
Primary completion
2011-10
Completion
2011-10

Outcome

Outcome not reported

Stopped (Enrollment): “No accrual in initial period, PI decided to close study.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 850 mg Oral
Background Docetaxel Small molecule 75 mg/m2 —
Background Prednisone Other / unclassified 5 mg Oral

Indications