drugset / Trial / NCT01478308
Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer
NaSingle-groupOpen-labelTreatment
Summary
This study is being conducted to determine the effectiveness of standard 3 weekly treatments using docetaxel and prednisone with metformin in patients with castration-resistant metastatic prostate cancer. It is also being conducted to determine the levels of toxicity of metformin when added to every 3 weekly docetaxel treatments in patients with endocrine resistent, metastatic prostate cancer.
Timeline
- Start
- 2011-06
- Primary completion
- 2011-10
- Completion
- 2011-10
Outcome
Outcome not reported
Stopped (Enrollment): “No accrual in initial period, PI decided to close study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 850 mg | Oral |
| Background | Docetaxel | Small molecule | 75 mg/m2 | — |
| Background | Prednisone | Other / unclassified | 5 mg | Oral |