drugset / Trial / NCT01482910

VEGF Trap-Eye: Investigation of Efficacy and Safety in Chinese Subjects With Wet AMD (Age-Related Macular Degeneration)

NCT01482910

Phase 3 Completed 304 enrolled Bayer Regeneron Pharmaceuticals · collab
RandomizedParallel-groupTriple-blindTreatment

Summary

This study will assess the efficacy and safety of intravitreally (IVT), i.e. directly into the eye administered VEGF Trap-Eye compared with photodynamic therapy (PDT) on visual function in Chinese subjects with age-related neovascular or "wet" age-related macular degeneration. Subjects will be randomized in a 3:1 ratio to either receive VEGF Trap-Eye or PDT. Both treatment groups will receive the other treatment as a sham procedure.

Timeline

Start
2011-12
Primary completion
2014-03
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Aflibercept Protein / enzyme biologic 2 mg Intravitreal
Comparator Verteporfin Other / unclassified

Indications